Careen \c(a)-reen\ as a girl's name is pronounced ke-REEN. Modern name. Possibly a combination of Cara with the -een suffix, or a variant of Corinne or Carina. Literary: first used in Margaret Mitchell's novel "Gone with the Wind" for Carreen. the younger sister of Scarlet. Sometimes used as a variant of Karen. Careen has 2 variant forms: Carreen and Karine. Baby names that sound like Careen are Caren, Careena, Carren, Carwen, Coreen and Kareen.