Edwena \e-dwe-na, ed-wena\ as a girl's name is a variant of Edwina (Old English), and the meaning of Edwena is "wealthy friend". The baby name Edwena sounds like Edeena, Edwyna, Edwiena and Edweena. Other similar baby names are Edana, Eden, Edenia, Edina, Edyna, Edna, Eddna, Edwinna, Edwine and Erwina.