Edwyna \e-dwy-na\ as a girl's name is a variant of Edwina (Old English), and the meaning of Edwyna is "wealthy friend". The baby name Edwyna sounds like Edyna and Edwena. Other similar baby names are Edana, Edina, Edeena, Edlyn, Edlynn, Edna, Eddna, Edwynne, Edwinna, Edwine, Edwiena, Edweena and Elayna.