Esmee \e-smee, es-mee\ as a girl's name is of French origin, and the meaning of Esmee is "esteemed". Esm?was originally a male name in Scotland. Literary: J.D. Salinger's short story "For Esm?ith Love and Squalor". Esmee has 4 variant forms: Esmae, Esmay, Esme and Isme. Baby names that sound like Esmee are Esmie and Esma.