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Keyes \ke-yes\ as a boy's name is of Old English origin. Probably an occupational name to do with the possession of keys. Also possibly from Kay "happy". Francis Scott Key, author of "The Star-Spangled Banner". Keyes has 2 variant forms: Key and Keys. For more information, see also related names Caius and Gaius. Baby names that sound like Keyes are Kees, Kasey, Kacey, Kasee, Kass, Kaycee and Kwesi. View a list of the 3 names that reference Keyes.