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Lourdes \lo(ur)-des\ as a girl's name is pronounced LOOR-des, LOORDZ. It is of French origin. Place name. Miracles of healing are attributed to the place in France where the Virgin Mary reportedly appeared in 1858 to a young girl, later honored as Saint Bernadette. Actress-singer Madonna chose the name for her first-born daughter. Ballerina Lourdes Lopez. Lourdes has 4 variant forms: Lourdecita, Lourdetta, Lourdette and Lurdes. View a list of the 2 names that reference Lourdes.